Reply To: Prolonged cataplexy and rapid Rx tolerance

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#10020
Jason
Jason
Keymaster
@jasonm

@capeofgoodhope usually an SNRI like effexor is used for cataplexy rather than an ssri.

You have not tried any other stimulants? Xyrem is a pain in the ass to get covered. It’s because the pharmaceutical company charges 13k per month for it. Personally, I found it horrible as a medication but others find it helpful. It’s very hard to tolerate the side effects for a lot of people. They used to give a 30 day supply for free. I don’t know if they still do.

Dexedrine is more wake promoting than adderall supposedly. I prefer it. It’s similar to adderall but has less side effects for me.

Focalin is another possible medicine you could try. It works differently.

Nuvigil is usually first line for sleepiness and it doesn’t have the rapid tolerance problem. My doctor did the clinical studies on it.